DMT

DMT is found in a variety of plants and is the psychoactive ingredient in the drug ayahuasca. In ayahuasca, a plant containing DMT is boiled together with a plant containing a monoamine oxidase inhibitor (MAOI) such as harmaline, and the mixture is drunk.⁴

When produced synthetically DMT is a white crystalline powder.³

Other names

Dimitri, The spirit molecule, Changa, Fantasia

How is DMT used?

DMT can be:

• vaporised or smoked in a pipe
• drunk as part of an ayahuasca brew
• snorted
• injected.⁵

Effects of DMT

There is no safe level of drug use. Use of any drug always carries some risk. It’s important to be careful when taking any type of drug. 

Psychedelics affect everyone differently, based on:

• size, weight and health
• whether the person is used to taking it
• whether other drugs are taken around the same time
• the amount taken
• the strength of the drug (varies from batch to batch)
• environment (where the drug is taken).

DMT affects everyone differently, but effects may include:

• a ‘rush’
• euphoria
• changes in mood
• increased sensitivity to bodily sensations (body aches, tingles, feelings of pain and pleasure, warmth and fatigue)6,7
• increased heart rate and blood pressure
• dilated pupils
• increased rectal temperature
• intense visual hallucination
• dissociation.^5,7

DMT is most commonly smoked in Australia, with effects commencing almost straight away and finishing after around 30 minutes.⁵

Impact of mood and environment

Drugs that affect a person’s mental state (psychoactive drugs) can also have varied effects depending on a person’s mood (often called the ‘set’) or the environment they are in (the ‘setting’):

• Set: a person’s state of mind, previous encounters with psychedelic drugs, and expectations of what’s going to happen. For example, feelings of stress or anxiety before using DMT may result in an unpleasant experience (bad trip).⁸
• Setting: the environment in which someone consumes a psychedelic drug – whether it’s known and familiar, who they’re with, if they’re indoors or outdoors, the type of music and light. For example, using DMT in a calm, quiet and relaxed environment can lead to, or contribute to, a pleasant experience but being in a noisy, crowded place may result in a negative experience.⁸
• Being in a good state of mind, with trusted friends and a safe environment before taking DMT reduces the risk of having a ‘bad’ trip.

Long-term effects

There have been no reports of toxic effects from the long-term use of DMT, aside from concerns regarding the cardiovascular impact of increased heart rate and blood pressure.¹

DMT and mental health 

DMT use can cause unpredictable negative reactions, such as:

• uncontrollable anxiety
• delusions and psychosis (particularly among people predisposed to mental health issues).